Explain The Etiological Models Of Schizophrenia Essay

Explain the etiological models of Schizophrenia. †¢ Genetic o Schizophrenia runs in families - higher rates in 1st degree relatives, especially if both parents schizophrenic, but those who suffer from schizophrenia are unlikely to reproduce o Heritability determined by concordance rates in twins, about 28% in monozygotic twins but only 6% dizygotic twins o Adoption studies confirm likely genetic component and show higher rates of schizophrenia in biological families o These family studies show that although there is a genetic component, other factors influence schizophrenia as well o Chromosomal/gene mapping has not been able to identify a specific gene or chromosome for schizophrenia o May be linked to chromosome 6 †¢ Physiological o Eye movement dysfunction ï‚ § Eye tracking dysfunction frequently seen in schizophrenic patients ï‚ § Poor smooth-pursuit eye tracking most common dysfunction, (instead of smoothly following the track of moving objects, schizophrenics exhibit jerky eye movements) ï‚ § Represents genetic marker of vulnerability to schizophrenia o Inhibition of event related potentials ï‚ § P50 phenomenon related to responses to auditory stimuli seen in many schizophrenics and their blood relatives ï‚ § Inability to inhibit certain responses may be source of various schizophrenic symptoms (distractibility, confusion, hallucinations) ï‚ § High P50 abnormality patients have larger deficits in attention and score more severely on assessment of negative symptoms ï‚ § May be linked toShow MoreRelatedMental Illnesses Explored : Schizophrenia1450 Words   |  6 PagesMental Illnesses Explored: Schizophrenia Schizophrenia has been associated with the dysregulation of many neurotransmitter systems. 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